Insignificant antifungal activity of plant extracts on Malassezia furfur

Abstract

Objective: The aim of present study was to investigate the antimalassezial potential of the
selected plant extracts known to possess medicinal values. Materials and Methods: The
crude extracts of five botanicals were evaluated against Malassezia furfur. The dried and
pulverized plant material was extracted with water and also successively extracted with
hexane, chloroform, and methanol, using the Soxhlet apparatus. The antimicrobial
activity assay was done by disk diffusion and 96‑well plate microdilution method.
Results: The results point toward the fact that all the tested extracts extracted in solvents
of different polarities exhibited no antifungal activity. Conclusion: The tested extracts
did not have, or had too little, antifungal activity to be used as a promising source of
novel antimicrobial substances against M. furfur.