The Role Of Immunological Factors In The Pathogenesis Of Hiv Infection In Women Of Reproductive Age With Genital Inflammatory Diseases

Abstract

Nowadays, there are a significant number of factors that determine the dynamics of the progression of the virus and the outcome of the disease. The main factor in the penetration of the virus into cells is cellular tropism, which is mediated by the determination of the viral phenotype and receptor interactions. But the mechanism of development of factors that contribute to the fact that the number of CD4+ T cells decreases and, at the same time, the number of X4-R5-tropic strains in AIDS increases, has not yet been fully understood.

A number of scientific studies are being carried out around the world to achieve high effectiveness of interventions aimed at the treatment and prevention of gynecological diseases in women living with HIV. In this regard, it is necessary to identify the main features of the development of diseases of the genital organs against the background of HIV infection and to substantiate the causes of the resulting negative changes.