Anti-Obesity Effect Of Bark Of Ficus Racemosa In High Fat Diet Induced Obese Rats
DOI:
https://doi.org/10.47750/pnr.2022.13.S05.51Keywords:
Udumber, Kurantaka, Barleria prionitis, Ficus racemosa, High fat diet induced obesity.Abstract
Method: In high fat diet induced obese rats, obesity-related characteristics, including body weight, serum biochemical parameters
were assessed. At the end of the experimental histological analysis were carried out. Obesity was induced in Wistar rats using a HFD
for first 25days. Then from 25th day to 50th day of study F. racemosa is given in dose of 90 mg/kg and 270mg/kg along with HFD. On
0, 25th, 50th day, body weight, histological changes and other parameters were recorded. Result: Bark powder of F.
racemosa significantly reduced the absolute body weight. Ingestion of HFD containing F. racemosa to rat exhibited reduction in lipid
parameters. High dose (270 mg/kg b.w) of F. racemosa significantly reduced the levels of triglyceride and VLDL whereas there were
few differences observed in LDL and cholesterol. Treatment groups do not exhibited any substantial decrease in BSL. Minimal
changes (+1) are found in liver tissues of F. racemose and B. prionitis treated groups. Furthermore, there is a mild fatty deposition is
found.
Conclusion: The results imply that F. racemose (at higher dose 270 mg/kg body) has anti-obesity effects in obesity-induced rats.
