Evaluation of the Serum Level of Cytokines IL-1B, IL-17 for some Patients with Acne Vulgaris in Baquba City
DOI:
https://doi.org/10.47750/pnr.2022.13.S01.89Keywords:
Acne Vulgaris, Level of Cytokines IL-1B , IL-17.Abstract
This study was conducted in Baqubah Teaching Hospital/Consulting Clinic which lasted from the beginning of September 2021 to the end of February، 2022, as the study aimed to investigate the serum level of some immunological parameters in patients with acne in Diyala
Governorate from these This study was conducted in Baqubah Teaching Hospital/Consulting Clinic which lasted from the beginning of September 2021 to the end of February، 2022, as the study aimed to investigate the serum level of some immunological parameters in
patients with acne in Diyala Governorate from these factors Interleukin 1 beta and Interleukin 17 (IL-17, IL-1B) by using ELISA technique,
The study included 90 individuals, where 58 blood samples were collected from acne patients after their diagnosis by the dermatologist specialized in the Dermatology Division at the Consulting Clinic. The number of males was (46) and the percentage of (79.4%) and the number of females was (12) and the percentage (20.6%), where the results showed a significant increase in males than in females, as well as the study included (32) apparently healthy individuals, 27 males and 5 females were considered as the control group. The results showed that the average age of acne sufferers was 18.879 years. The study also showed that the highest age group affected by acne for males and females is (15-20) years.
The study showed that the levels of cellular kinetics were represented in that the concentration of IL-1B in the serum of acne patients was higher than its concentration in the serum of the healthy group, as the mean ± standard deviation was (128.56 ± 71.06 and 114.86 ± 47.81) pg/ml respectively.
The study also showed an increase in the concentration of IL-17 in the serum of acne patients than in the serum of the healthy group, and this increase was not statistically significant, and the mean ± standard deviation of the group of patients was (37.86 ±23.24) Pg/ml and the healthy group was (26.03 ±15.58) Pg/ml .
