In Vitro Antioxidant And Anticancer Activity Of Nigella Sativa, Anethum Sowa And Berberis Aristata Herbal Formulation Using MCF-7 Cell Line

Abstract

Several herbs and plants are well-known for their medicinal and therapeutic properties. We intended to test that the formulation of Nigella sativa, Anethum sowa and Berberis aristata herbal formulation as aqueous and ethanol extracts have got antioxidant and anticancer activities. Equal quantities of each plant powder were mixed and subjected to aqueous and ethanol solvents for 72 hours by maceration procedure. The extract obtained was used for further studies. Different forms of assays like MTT, ABTS, GCMS and anticancer activities on MCF -7 cell lines were performed. Significant anti-oxidant, free radical scavenging and anticancer activities were noticed in the mixture. The anticancer activity was higher than individual described herbs. We suggest that synchronized action by a mixture of herbs could prove more beneficial in drug concepts than individual drugs.