A Review Article Titled Improve Survival With Appropriate Timing Of Diagnostic Ct-Scan In Colorectal Patients With Anastomotic Leakage

Authors

  • Sonika Kumari, Fauzia Khan, Mamta Verma, Bhawna Solanki, Neelam Rao Bharti , Pushpender Kumar Rajput

DOI:

https://doi.org/10.47750/pnr.2022.13.S08.533

Abstract

Anastomotic leakage (AL), a dreaded side effect of colorectal surgery, is linked to higher morbidity and mortality rates. Although surgical technology has advanced, the reported risk of 1-22% is still considerable. AL causes a permanent enterostomy, additional surgery, and extended hospitalization. Additionally, it results in a worse 5-year survival rate and increased mortality (10–16%) in the early postoperative term. The pathophysiology of AL is still unknown despite considerable research examining the connection between patient risk factors, AL, and various surgical approaches. The prognosis of AL is significantly influenced by early diagnosis, ideally before symptoms appear. Although the C-reactive protein (CRP) level has been studied as a PR symptomatic marker, its prognostic significance is still debatable. Patients with AL frequently experience fever, ileus, and discomfort, although these clinical indicators of a systemic inflammatory response are not highly specific.

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Published

2023-01-04 — Updated on 2023-01-05

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How to Cite

A Review Article Titled Improve Survival With Appropriate Timing Of Diagnostic Ct-Scan In Colorectal Patients With Anastomotic Leakage. (2023). Journal of Pharmaceutical Negative Results, 4222-4224. https://doi.org/10.47750/pnr.2022.13.S08.533 (Original work published 2023)