EFFECT OF AEGLE MARMELOS LEAF EXTRACT ON GLUCOSE UPTAKE USING ISOLATED RAT DIAPHRAGM

Abstract

The plant extract of the aegle marmelos, a medicinal plant was used for the solely purpose to know whether is it any better or equal to the standard diabetic drug rosiglitazone by using the isolated diaphragm of the rat. Tyrode solution was prepared and accordingly extracts were divided into7 groups with those comparing with glucose concentration of the drug after the tissue was added with standard drug and with leaf extract, leaf extract of 0.1mg and 1 mg ,5mg and 10mg was taken. Results showed that only 10mg leaf extract had show a significant uptake of the glucose which is equal to uptake of standard drug.