Neurofibromatosis Type- I A Rare Case Report And Literature Review On Its Oral Manifestations.

Abstract

Neurofibromatosis (NF) refers to a group of genetic disorders that predominantly affect neural tissues. About 90% of all cases of neurofibromatosis are caused by neurofibromatosis type 1 (NF1), also called von Recklinghausen's disease. In 3,000 births, one case of this genetic disease can be found. There is an extremely wide range of expressivity of NF1, with manifestations ranging from moderate lesions to several complications and functional impairments. The condition is associated with oral manifestations in almost 72% of NF1 sufferers. The aim of this article is to report the case of NF1 with different oral and Dental orthopantomography characteristic features to review the literature.