The Effect of Mechanical Ventilation Mode on Blood Loss in Endoscopic Sinus Surgery, A Randomized Clinical Study

Abstract

Background: One of the important problem during endoscopic sinus surgery is bleeding. Bleeding causes disruption of the surgical field and damages the base of the skull and the eye cavity and consequently increases the duration of surgery vasopressor drugs may cause instability of hemodynamic, specially, in hypertension patients or patients with ischemic heart. Hypotension induction with various drugs causes to use a greater amount of anesthetic drugs and its side effects. Therefore, it is necessary to find a treatment for this complication. We decided to do a study on two modes of ventilation to reduce bleeding and increasing surgery satisfaction.
Methods: This investigation was performed on 134 patients. They were candidates of endoscopic sinus surgery 67 in volume mechanical ventilation group and 67 in pressure mechanical ventilation group. Patients were divided randomly in two groups and were recorded vital signs, complications, and bleeding. We used ANOVA and Chi-square tests to compare the data.
Results: The findings indicated that there is not significant difference between VCV and PCV in duration of surgery, intraoperative bleeding, heart rate, mean arterial blood pressure and surgeon satisfaction (P>0.05).
Conclusion: Various methods of ventilation did not show significant difference in bleeding and due to inconsistencies in the results of the current study and some studies and due to the limitations of the studies, further studies with higher numbers of specimens are recommended.