Ocular Drug Delivery With Special Reference To Natural Polymer

Abstract

Because of the distinctive anatomical and physiological barriers, ocular medication administration is a particularly difficult task. The scientists were required to create novel formulation to medications to ocular tissues at a controlled rate to decrease the frequency of instillations due to the low ocular bioavalibility  (10%) obtained from standard formulation. Natural polymers have demonstrated the ability to topically deliver medications throughout the small precorneal region and discharge them over an extended period of time. The discussion covers the key elements that must be taken into account when creating ophthalmic formulations, such as the features of the drug molecule and the polymer that influence the release rate. Chitosan, Polyvinyl alcohol, Sodium alginate, and Nanocrystalline cellulose are examples of novel polymers.