Study The Pharmacological Activity Of Methanolic Extract Of Cercis Siliquastrum L. Leaves On Animal Model

Authors

  • Asmaa M H Al Ali
  • Faten S Mounce
  • Nadheerah F. Neamah

DOI:

https://doi.org/10.47750/pnr.2022.13.S02.35

Keywords:

Analgesic; Cercis siliquastrum; Anti-inflammatory; Gastrointestinal; Antidepressant activity

Abstract

Cercis siliquastrum (Judas tree) is a commonly used traditional medicine in Iraq with drug discovery potential. The aim of this study
was to investigate the in vivo acutes toxicity, analgesic activity by acetic acid induced writhing model, Anti-inflammatory by
Carrageenan induced paw edema method, gastrointestinal tract (GIT) motility by charcoal meal protocol, antidepressant activity by
using forced swimming test (FST) model of methanolic extract Cercis siliquastrum L. leaves (MECSL). Differenet concentration of
MECSL curde extract was used (50 mg/kg, 150 mg/kg, 300 mg/kg. The results revealed that Cercis siliquastrum methanloic extract is
dose dependent. Crude MECSL extract proved a strong analgesic, anti-inflammatory, and properties.

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Published

2022-10-05

Issue

Vol. 13 SPECIAL ISSUE 02 (2022)

Section

Articles

How to Cite

Study The Pharmacological Activity Of Methanolic Extract Of Cercis Siliquastrum L. Leaves On Animal Model. (2022). Journal of Pharmaceutical Negative Results, 250-254. https://doi.org/10.47750/pnr.2022.13.S02.35