Assessing The Impact Of Platelet Transfusions OnOutcomes In Patients With Chemotherapy Induced Thrombocytopenia

Abstract

Background: CIT is defined as a triggering of thrombocytopenia in cancer patients undergoing chemotherapy and the threat of bleeding is significantly high among the suffering patients. Platelet transfusions are normally used in the management of the condition considering the dangers posed by bleeding and the desire to enhance safety and effectiveness of the patients. It is imperative to understand the effectiveness of these two structures so as to enhance patient care.

Objectives : In order to assess the benefits of platelet transfusions in the treatment of patients with thrombocytopenia related to chemotherapy in terms of prognosis and rates of bleeding, and to determine the effect of the transfusions on patients’ recovery.

Study design: A Cross Sectional Study.

Place and duration of study. Department of Pathology Watim medical and dental college, rawat from Sep 2021 to Dec 2021

Methods :In this study the participants were 150 patients who had thrombocytopenia due to chemotherapy and were treated with platelet transfusions. Frequency of transfusion, bleeding incidence and recuperative time were recorded systematically. For the purpose of evaluating effects of platelet transfusions on rates of bleeding and mortality, permitting an evidence-based approach to transfusion decision, SPSS 24. 0 statistical tests were used.

Results : Out of the 150 patients, the cross-sectional mean of number of platelet transfusions given was 3. 2, standard deviation, ±1. 1. The level of the bleeding complications was reduced after transfusions (p < 0. 01). The time to recovery also increased significantly, 10. 5 days (SD ±3. 2) after the transfusion in compared with 14. 8 days (SD ±4. 0) before transfusion.

Conclusion : Platelet transfusions are very effective in decreasing the incidences of bleeding as well as shortening the duration of recovery among patients with chemotherapy-induced thrombocytopenia. The following results have endorsed the platelet transfusion as an effective treatment for CIT and the improvement of patients’ prognosis during chemotherapy.